articleTop 1% cited
KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours
European Journal of Cancer · 2006 · Vol. 42(8) · pp. 1093–1103
Maria Dêbiec‐Rychter✉(KU Leuven)Raf Sciot(KU Leuven)Axel Le Cesne(Institut Gustave Roussy)M. Schlemmer(Institute of Groundwater Ecology)Peter Hohenberger(Charité - Universitätsmedizin Berlin)Allan T. van Oosterom(KU Leuven)Jean‐Yves Blay(Centre Léon Bérard)Serge Leyvraz(University Hospital of Lausanne)Michel Stul(KU Leuven)Paolo G. Casali(Fondazione IRCCS Istituto Nazionale dei Tumori)John Zalcberg(Peter MacCallum Cancer Centre)Jaap Verweij(Erasmus MC)M. van Glabbeke(European Organisation for Research and Treatment of Cancer)Anne Hagemeijer(KU Leuven)Ian Judson(Royal Marsden Hospital)
Gastrointestinal Tumor Research and TreatmentGastrointestinal disorders and treatmentsSarcoma Diagnosis and TreatmentPDGFRAImatinibInternal medicineMedicineImatinib mesylateExonOncologyGiSTRelative riskGastroenterology
MeSH terms
Imatinib MesylateAdultAgedAntineoplastic AgentsBenzamidesExonsFemaleGenotypeHumansMaleMiddle AgedMutationPiperazinesPrognosisPyrimidines
Funding
- American Lebanese Syrian Associated Charities
Citations
894
FWCI
37.46
field-weighted impact
References
25
Percentile
100%
vs. same field & year
Citations per year
References
KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors
American Journal Of Pathology · 2000 · 646 citations
Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations
Human Pathology · 2002 · 455 citations
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells
Nature Medicine · 1996 · 3,643 citations
Mutations in Exon 11 of c-Kit Occur Preferentially in Malignant versus Benign Gastrointestinal Stromal Tumors and Do Not Occur in Leiomyomas or Leiomyosarcomas
American Journal Of Pathology · 1999 · 550 citations
Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor
Journal of Clinical Oncology · 2003 · 2,287 citations
Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
Journal of Pharmacology and Experimental Therapeutics · 2000 · 1,280 citations
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