reviewTop 1% cited
Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations
Human Pathology · 2002 · Vol. 33(5) · pp. 484–495
Michael C. Heinrich✉(Columbia University)Brian P. Rubin(Columbia University)B. Jack Longley(Dana-Farber Cancer Institute)Jonathan A. Fletcher(Brigham and Women's Hospital)
Gastrointestinal Tumor Research and TreatmentGastrointestinal disorders and treatmentsMast cells and histamineBiologyStromal cellReceptor tyrosine kinaseCancer researchGiSTProto-Oncogene Proteins c-kitPoint mutationSignal transductionMutationGenetics
MeSH terms
Chromosome AberrationsFemaleGastrointestinal NeoplasmsHumansKaryotypingMaleSarcomaSignal TransductionGene Expression Regulation, NeoplasticStromal CellsProto-Oncogene Proteins c-kit
Citations
455
FWCI
27.10
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75
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100%
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References
KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors
American Journal Of Pathology · 2000 · 646 citations
Mutations in Exon 11 of c-Kit Occur Preferentially in Malignant versus Benign Gastrointestinal Stromal Tumors and Do Not Occur in Leiomyomas or Leiomyosarcomas
American Journal Of Pathology · 1999 · 550 citations
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