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A mutation in the ligand binding domain of the androgen receptor of human INCaP cells affects steroid binding characteristics and response to anti-androgens

Biochemical and Biophysical Research Communications · 1990 · Vol. 173(2) · pp. 534–540

Jos Veldscholte✉(Erasmus University Rotterdam)C. Ris-Stalpers(Erasmus University Rotterdam)George G. J. M. Kuiper(Erasmus University Rotterdam)Guido Jenster(Erasmus University Rotterdam)Cor Berrevoets(Erasmus University Rotterdam)Eric ClaassenH.C.J. van Rooij(Erasmus University Rotterdam)Jan Trapman(Erasmus University Rotterdam)Albert O. Brinkmann(Erasmus University Rotterdam)E. Mulder(Erasmus University Rotterdam)

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Prostate Cancer Treatment and Research Mass Spectrometry Techniques and Applications Estrogen and related hormone effectsAndrogen receptorAndrogenEndocrinologyRNF4Internal medicineBiologyPoint mutationAndrogen insensitivity syndromeTransfectionReceptor

MeSH terms

Binding SitesBinding, CompetitiveHeLa CellsHumansLigandsMaleMutationProstatic NeoplasmsReceptors, AndrogenSteroidsTransfectionTumor Cells, CulturedGene Expression Regulation, Neoplastic

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941

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24.60

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Androgen Receptor in Prostate Cancer