reviewTop 1% cited

The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry

Journal of Immunological Methods · 2009 · Vol. 347(1-2) · pp. 3–11

Andrew N. Hoofnagle✉(University of Washington Applied Physics Laboratory)Mark H. Wener(University of Washington)

Mass Spectrometry Techniques and Applications Advanced Proteomics Techniques and Applications Biosensors and Analytical DetectionAnalyteTandem mass spectrometryImmunoassayMass spectrometryComputer scienceComputational biologyBiochemical engineeringChromatographyChemistryMedicine

MeSH terms

Antibodies, HeterophileAutoantibodiesDose-Response Relationship, ImmunologicHumansImmunoassayPredictive Value of TestsQuality ControlThyroglobulinReproducibility of ResultsBiomarkersArtifactsMedical ErrorsTandem Mass Spectrometry

Funding

National Cancer Institute

Citations

549

FWCI

11.13

field-weighted impact

References

Percentile

99%

vs. same field & year

Citations per year

Cited by

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References

Human Anti-Animal Antibody Interferences in Immunological Assays

Clinical Chemistry · 1999 · 584 citations

Electrospray interface for liquid chromatographs and mass spectrometers

Analytical Chemistry · 1985 · 1,491 citations

Mass Spectrometric Quantitation of Peptides and Proteins Using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA)

Journal of Proteome Research · 2004 · 798 citations

Ion Suppression in Mass Spectrometry

Clinical Chemistry · 2003 · 1,568 citations

IMMUNOASSAY OF ENDOGENOUS PLASMA INSULIN IN MAN

Journal of Clinical Investigation · 1960 · 3,029 citations

Multi-analyte immunoassay

Journal of Pharmaceutical and Biomedical Analysis · 1989 · 296 citations

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