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Ion Suppression in Mass Spectrometry

Clinical Chemistry · 2003 · Vol. 49(7) · pp. 1041–1044

Thomas M Annesley✉(University of Michigan–Ann Arbor)

Abstract

Whenever mass spectrometric assays are developed, ion suppression studies should be performed using expected physiologic concentrations of the analyte under investigation.

Mass Spectrometry Techniques and Applications Pesticide Residue Analysis and Safety Metabolomics and Mass Spectrometry StudiesAnalyteMass spectrometryIon suppression in liquid chromatography–mass spectrometryChemistryIonReagentChromatographyIonizationAnalytical Chemistry (journal)Evaporation

MeSH terms

Chromatography, High Pressure LiquidDetergentsPharmaceutical PreparationsIndicators and ReagentsIonsProteinsSaltsSensitivity and SpecificityMass Spectrometry

Citations

1,568

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23.11

field-weighted impact

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Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)