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Human Anti-Animal Antibody Interferences in Immunological Assays

Clinical Chemistry · 1999 · Vol. 45(7) · pp. 942–956
Larry J. Kricka

Abstract

Human anti-animal antibodies often go unnoticed, to the detriment of patient care. A heightened awareness on the part of laboratory staff and clinicians of the problems caused by this type of interference in routine immunoassay tests is desirable. Efforts should be directed at improving methods for identifying and eliminating this type of analytical interference.

Monoclonal and Polyclonal Antibodies ResearchProtein purification and stabilityViral Infectious Diseases and Gene Expression in InsectsAntibodyImmunoassayImmunologyMonoclonal antibodyBiologySerologyPrimary and secondary antibodiesPopulationMedicine

MeSH terms

AnimalsAntibodiesAntibodies, MonoclonalAntibody SpecificityBody FluidsFalse Negative ReactionsFalse Positive ReactionsHumansImmunoassayMice
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