article Open AccessTop 1% cited
Rescue Surgery for Unresectable Colorectal Liver Metastases Downstaged by Chemotherapy
Annals of Surgery · 2004 · Vol. 240(4) · pp. 644–658
René Adam✉(Hôpital Paul-Brousse)V. Delvart(Hôpital Paul-Brousse)Gérard Pascal(Hôpital Paul-Brousse)Adrian Valeanu(Hôpital Paul-Brousse)Denis Castaing(Hôpital Paul-Brousse)Daniel Azoulay(Hôpital Paul-Brousse)Sylvie Giacchetti(Hôpital Paul-Brousse)Bernard Paule(Hôpital Paul-Brousse)F Kunstlinger(Hôpital Paul-Brousse)O Ghémard(Hôpital Paul-Brousse)Françis Lévi(Hôpital Paul-Brousse)Henri Bismuth(Hôpital Paul-Brousse)
Abstract
Modern chemotherapy allows 12.5% of patients with unresectable CRLM to be rescued by liver surgery. Despite a high rate of recurrence, 5-year survival is 33% overall, with a wide use of repeat hepatectomies and extrahepatic resections. Four preoperative risk factors could select the patients most likely to benefit from this strategy.
Hepatocellular Carcinoma Treatment and PrognosisColorectal Cancer Treatments and StudiesCholangiocarcinoma and Gallbladder Cancer StudiesMedicineOxaliplatinChemotherapyIrinotecanSurgeryColorectal cancerMultivariate analysisHepatectomyInternal medicineOncology
MeSH terms
OxaliplatinAdultAgedAged, 80 and overAntimetabolites, AntineoplasticAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsLeucovorinFemaleFluorouracilFollow-Up StudiesForecastingHepatectomyHumansLiver Neoplasms
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