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Chemotherapy-associated hepatotoxicity and surgery for colorectal liver metastases

British journal of surgery · 2007 · Vol. 94(3) · pp. 274–286
Daria ZorziAlexis LaurentTimothy M. PawlikGregory Y. LauwersJean‐Nicolas VautheyEddie K. Abdalla

Abstract

Preoperative chemotherapy for CLM induces regimen-specific hepatic changes that can affect patient outcome. Both response rate and toxicity should be considered when selecting preoperative chemotherapy in patients with CLM.

Hepatocellular Carcinoma Treatment and PrognosisColorectal Cancer Treatments and StudiesLiver Disease Diagnosis and TreatmentMedicineChemotherapyColorectal cancerHepatectomyGeneral surgerySurgeryInternal medicineOncologyGastroenterologyCancer

MeSH terms

Antineoplastic AgentsFatty LiverHepatectomyHepatic Veno-Occlusive DiseaseHumansLiverLiver NeoplasmsColorectal NeoplasmsChemotherapy, Adjuvant
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Chemotherapy-associated hepatotoxicity and surgery for colorectal liver metastases · Scinovex