articleTop 1% cited
Weight loss increases circulating levels of ghrelin in human obesity
Clinical Endocrinology · 2002 · Vol. 56(2) · pp. 203–206
Troels Krarup Hansen✉(Aarhus University Hospital)Rolf Dall(Aarhus University Hospital)Hiroshi Hosoda(National Cerebral and Cardiovascular Center)Masayasu Kojima(National Cerebral and Cardiovascular Center)Kenji Kangawa(National Cerebral and Cardiovascular Center)Jens Sandahl Christiansen(Aarhus University Hospital)Jens Otto Lunde Jørgensen(Aarhus University Hospital)
Abstract
This study provides evidence of a reversible suppression of ghrelin associated with obesity. The feasibility of measuring ghrelin in the circulation provides a new tool for the investigation of the complex hormonal regulation of appetite and energy balance.
Regulation of Appetite and ObesityBiochemical Analysis and Sensing TechniquesDiet and metabolism studiesGhrelinInternal medicineEndocrinologyWeight lossAppetiteObesityGrowth hormone secretagogue receptorHormoneMedicineLeptin
MeSH terms
Analysis of VarianceBody CompositionFemaleHumansMiddle AgedObesityPeptidesGrowth HormoneWeight LossPeptide HormonesGhrelin
Funding
- Aarhus Universitetshospital
- Hospital Research Foundation
- Aarhus Universitets Forskningsfond
Citations
495
FWCI
11.91
field-weighted impact
References
11
Percentile
99%
vs. same field & year
Citations per year
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References
Ghrelin and Des-acyl Ghrelin: Two Major Forms of Rat Ghrelin Peptide in Gastrointestinal Tissue
Biochemical and Biophysical Research Communications · 2000 · 923 citations
Circulating Ghrelin Levels Are Decreased in Human Obesity
Diabetes · 2001 · 2,003 citations
The Novel Hypothalamic Peptide Ghrelin Stimulates Food Intake and Growth Hormone Secretion
Endocrinology · 2000 · 1,548 citations
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Nature · 1999 · 8,427 citations
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