review Open AccessTop 1% cited
Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
Developmental Cell · 2008 · Vol. 14(6) · pp. 818–829
Jing Yang✉(University of California, San Diego)Robert A. Weinberg✉(Massachusetts Institute of Technology)
Wnt/β-catenin signaling in development and cancerHippo pathway signaling and YAP/TAZCancer Cells and MetastasisAdherens junctionBiologyEpithelial–mesenchymal transitionMorphogenesisCell biologyMesenchymal stem cellMetastasisCell migrationCell junctionCell polarity
MeSH terms
AnimalsCell MovementEpithelial CellsHumansMesodermModels, BiologicalNeoplasm MetastasisNeoplasmsSignal TransductionEmbryonic Development
Funding
- Breast Cancer Research Foundation
- Sidney Kimmel Foundation for Cancer Research
- Massachusetts Institute of Technology
- National Institutes of Health
- Ludwig Center for Molecular Oncology
Citations
3,016
FWCI
59.72
field-weighted impact
References
120
Percentile
100%
vs. same field & year
Citations per year
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References
Wnt/β-catenin signaling in cancer stemness and malignant behavior
Current Opinion in Cell Biology · 2007 · 782 citations
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
Nature Cell Biology · 2007 · 1,544 citations
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition
Nature Cell Biology · 2004 · 1,569 citations
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
Nature reviews. Cancer · 2007 · 3,063 citations
Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
Cancer Research · 2008 · 1,509 citations
The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion
Molecular Cell · 2001 · 1,374 citations
Epithelial–mesenchymal transitions in tumour progression
Nature reviews. Cancer · 2002 · 6,649 citations
The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression
Nature Cell Biology · 2000 · 3,610 citations
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