articleTop 10% cited

Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist

European Journal of Pharmacology · 1988 · Vol. 150(1-2) · pp. 9–14

Raimo Virtanen✉(University of Eastern Finland)Juha‐Matti Savola(University of Oulu)Veijo Saano(University of Eastern Finland)Leena Nyman

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Receptor Mechanisms and Signaling Neuroscience and Neuropharmacology Research Anesthesia and Sedative AgentsMedetomidineIdazoxanChemistryAgonistYohimbinePrazosinAlpha-2 adrenergic receptorAtipamezolePharmacologyClonidine

MeSH terms

Brimonidine TartrateAdrenergic alpha-AgonistsAnimalsAntihypertensive AgentsBrainClonidineFemaleImidazolesMaleMuscle, SmoothMydriaticsPrazosinQuinoxalinesRats, Inbred StrainsVas Deferens

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692

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4.91

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96%

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Cited by

Sedative, Amnestic, and Analgesic Properties of Small-Dose Dexmedetomidine Infusions

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References

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

Journal of Biological Chemistry · 1951 · 317,666 citations

A functional basis for classification of α-adrenergic receptors

Life Sciences · 1977 · 802 citations

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Biochemical Pharmacology · 1973 · 12,855 citations

Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist

European Journal of Pharmacology · 1988 · 692 citations

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