article Open AccessTop 1% cited
The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer
Breast Cancer Research and Treatment · 2013 · Vol. 139(3) · pp. 667–676
Simone Muenst✉(Hospital Base)Savas D. Soysal(Washington University in St. Louis)Feng Gao(Washington University in St. Louis)Ellen C. Obermann(University Hospital of Basel)Daniel Oertli(Hospital Base)W.E. Gillanders(Washington University in St. Louis)
Cancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesCancer Cells and MetastasisBreast cancerMedicineCancerTumor-infiltrating lymphocytesImmunohistochemistryOncologyTissue microarrayLymph nodeInternal medicineAntibody
MeSH terms
AgedAged, 80 and overBreast NeoplasmsFemaleHumansMiddle AgedPrognosisReceptors, ImmunologicSurvival AnalysisLymphocytes, Tumor-InfiltratingReceptor, ErbB-2Erb-b2 Receptor Tyrosine KinasesTissue Array AnalysisProgrammed Cell Death 1 Receptor
Funding
- Alvin J. Siteman Cancer Center
- National Cancer Institute
Citations
342
FWCI
12.08
field-weighted impact
References
48
Percentile
99%
vs. same field & year
Citations per year
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References
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Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
Blood · 2009 · 1,751 citations
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
Nature Medicine · 2002 · 4,970 citations
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Immunity · 1994 · 2,184 citations
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Breast Cancer Research and Treatment · 2006 · 806 citations
Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies
PLoS Medicine · 2010 · 1,150 citations
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK)
JNCI Journal of the National Cancer Institute · 2005 · 2,064 citations
Molecular portraits of human breast tumours
Nature · 2000 · 16,173 citations
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