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A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C

Journal of Hepatology · 2013 · Vol. 59(1) · pp. 81–88
Bruno SangroCarlos Gómez-MartínManuel de la MataMercedes IñarrairaeguiElena GarraldaPilar BarreraJosé Ignacio Riezu‐BojEsther LarreaCarlos AlfaroPablo SarobeJuan José LasarteJosé Luis Perez‐GraciaIgnacio MeleroJesús Prìeto
Hepatitis C virus researchCancer Immunotherapy and Biomarkersinterferon and immune responsesTremelimumabMedicineHepatocellular carcinomaInternal medicineImmunologyCirrhosisHepatitis CGastroenterologyAdverse effectHepatitis C virus

MeSH terms

AgedAntibodies, MonoclonalAntineoplastic AgentsAntiviral AgentsFemaleCarcinoma, HepatocellularHumansLiver CirrhosisLiver NeoplasmsMaleMiddle AgedPilot ProjectsHepacivirusViral LoadHepatitis C, Chronic

Funding

  • Pfizer
  • Instituto de Salud Carlos III
Citations
982
FWCI
18.97
field-weighted impact
References
39
Percentile
100%
vs. same field & year
Citations per year
References
Sorafenib in Advanced Hepatocellular Carcinoma
New England Journal of Medicine · 2008 · 12,835 citations
The blockade of immune checkpoints in cancer immunotherapy
Nature reviews. Cancer · 2012 · 13,550 citations
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
New England Journal of Medicine · 2010 · 15,037 citations
New Guidelines to Evaluate the Response to Treatment in Solid Tumors
JNCI Journal of the National Cancer Institute · 2000 · 15,689 citations
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
Journal of Hepatology · 2018 · 11,335 citations
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