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article Open AccessTop 10% cited

BS-Seeker2: a versatile aligning pipeline for bisulfite sequencing data

BMC Genomics · 2013 · Vol. 14(1) · pp. 774–774
Weilong GuoPetko FizievWeihong YanShawn CokusXueguang SunMichael Q. ZhangPao‐Yang ChenMatteo Pellegrini

Abstract

Our evaluations on the performance show that BS-Seeker2 works efficiently and accurately for both WGBS data and RRBS data. BS-Seeker2 is freely available at http://pellegrini.mcdb.ucla.edu/BS_Seeker2/ and the Galaxy server.

Epigenetics and DNA MethylationRNA modifications and cancerCancer-related gene regulationBisulfite sequencingComputational biologyBisulfiteDNA methylationBiologyPipeline (software)DNA sequencingComputer scienceMethylated DNA immunoprecipitationDNA

MeSH terms

HumansSoftwareSulfitesGenome, HumanSequence AlignmentSequence Analysis, DNACpG IslandsDNA MethylationHigh-Throughput Nucleotide Sequencing

Funding

  • National Natural Science Foundation of China
  • China Scholarship Council
Citations
453
FWCI
9.72
field-weighted impact
References
19
Percentile
99%
vs. same field & year
Citations per year
References
BSMAP: whole genome bisulfite sequence MAPping program
BMC Bioinformatics · 2009 · 1,296 citations
SOAP: short oligonucleotide alignment program
Bioinformatics · 2008 · 3,664 citations
Galaxy: A platform for interactive large-scale genome analysis
Genome Research · 2005 · 2,058 citations
Fast gapped-read alignment with Bowtie 2
Nature Methods · 2012 · 59,710 citations
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