article Open Access
Galaxy: A platform for interactive large-scale genome analysis
Genome Research · 2005 · Vol. 15(10) · pp. 1451–1455
Belinda Giardine✉(Pennsylvania State University)Cathy Riemer(Pennsylvania State University)Ross C. Hardison(Pennsylvania State University)Richard Burhans(Pennsylvania State University)Laura Elnitski(National Human Genome Research Institute)Prachi Shah(Pennsylvania State University)Yi Zhang(Pennsylvania State University)Daniel Blankenberg(Pennsylvania State University)István Albert(Pennsylvania State University)James Taylor(Pennsylvania State University)Webb Miller(Pennsylvania State University)W. James Kent(University of California, Santa Cruz)Anton Nekrutenko(Pennsylvania State University)
Abstract
Accessing and analyzing the exponentially expanding genomic sequence and functional data pose a challenge for biomedical researchers. Here we describe an interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results. The heart of Galaxy is a flexible history system that stores the queries from each user; performs operations such as intersections, unions, and subtractions; and links to other computational tools. Galaxy can be accessed at http://g2.bx.psu.edu.
Genomics and Phylogenetic StudiesGene expression and cancer classificationAlgorithms and Data CompressionAnnotationBiologyComputer scienceGenomeGalaxySimple (philosophy)VisualizationComputational biologyWorld Wide WebInformation retrieval
MeSH terms
Biological EvolutionPromoter Regions, GeneticGenomeInternetDatabases, Genetic
Funding
- University of Pennsylvania
- Pennsylvania State University
- National Institutes of Health
- Huck Institutes of the Life Sciences
Citations
2,058
FWCI
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field-weighted impact
References
23
Percentile
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vs. same field & year
Citations per year
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