article Open AccessTop 10% cited
Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis
Journal of Investigative Dermatology · 2009 · Vol. 129(9) · pp. 2175–2183
Erin G. Harper(Oregon Health & Science University)Changsheng GuoHeather L. Rizzo(Oregon Health & Science University)Joseph V. Lillis(Oregon Health & Science University)Stephen E. KurtzIliyana Skorcheva(Oregon Health & Science University)David E. Purdy(Oregon Health & Science University)Erin Fitch(Oregon Health & Science University)Mihail S. Iordanov(Oregon Health & Science University)Andrew Blauvelt✉(Oregon Health & Science University)
Psoriasis: Treatment and PathogenesisDermatology and Skin DiseasesAsthma and respiratory diseasesCCL20PsoriasisC-C chemokine receptor type 6ChemokineTumor necrosis factor alphaImmunologyKeratinocyteCCL17Interleukin 17Cytokine
MeSH terms
Interleukin-22AnimalsCells, CulturedEpidermisHumansInterleukinsMice, Inbred BALB CPsoriasisTumor Necrosis Factor-alphaKeratinocytesInterleukin-17MiceReceptors, CCR6Chemokine CCL20
Funding
- U.S. Department of Veterans Affairs
- National Institutes of Health
Citations
499
FWCI
9.89
field-weighted impact
References
43
Percentile
99%
vs. same field & year
Citations per year
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References
Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells
Journal of Investigative Dermatology · 2008 · 1,064 citations
IL‐22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis
European Journal of Immunology · 2006 · 908 citations
Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cells
Nature Immunology · 2007 · 1,798 citations
A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes
The American Journal of Human Genetics · 2007 · 1,080 citations
Phenotypic and functional features of human Th17 cells
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Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells
Nature Immunology · 2007 · 1,799 citations
Development, cytokine profile and function of human interleukin 17–producing helper T cells
Nature Immunology · 2007 · 2,001 citations
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