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Meta‐analysis of smooth muscle relaxants in the treatment of irritable bowel syndrome

Alimentary Pharmacology & Therapeutics · 2001 · Vol. 15(3) · pp. 355–361
Thierry PoynardCorinne RegimbeauY. Benhamou

Abstract

According to this overview five drugs have proved their clinical efficacy in patients with irritable bowel syndrome, without significant adverse reactions: cimetropium bromide, pinaverium bromide, trimebutine, octilium bromide and mebeverine.

Gastrointestinal motility and disordersPathogenesis and Treatment of HiccupsComplementary and Alternative Medicine StudiesMedicinePlaceboIrritable bowel syndromeOdds ratioInternal medicineClinical trialRandomized controlled trialAdverse effectAnesthesiaGastroenterology

MeSH terms

AdultColonic Diseases, FunctionalFemaleHumansMaleMiddle AgedParasympatholyticsPlacebosAbdominal PainOdds RatioTreatment Outcome
Citations
405
FWCI
24.08
field-weighted impact
References
61
Percentile
100%
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