article Open AccessTop 1% cited
Targeting breast stem cells with the cancer preventive compounds curcumin and piperine
Breast Cancer Research and Treatment · 2009 · Vol. 122(3) · pp. 777–785
Madhuri Kakarala✉(Michigan Medicine)Dean E. Brenner(Ann Arbor VA Medical Center)Hasan Körkaya(University of Michigan–Ann Arbor)Connie Cheng(University of Michigan–Ann Arbor)Karim Tazi(University of Michigan–Ann Arbor)Christophe Ginestier(University of Michigan–Ann Arbor)Suling Liu(University of Michigan–Ann Arbor)Gabriela Dontu(University of Michigan–Ann Arbor)Max S. Wicha(University of Michigan–Ann Arbor)
Genomics, phytochemicals, and oxidative stressPiperaceae Chemical and Biological StudiesCurcumin's Biomedical ApplicationsCurcuminPiperineWnt signaling pathwayStem cellCancer stem cellProgenitor cellCancer researchBreast cancerPharmacologyBiology
MeSH terms
Aldehyde DehydrogenaseAlkaloidsAntineoplastic Combined Chemotherapy ProtocolsBreastBreast NeoplasmsCell DifferentiationCells, CulturedCurcuminFemaleHumansImmunoenzyme TechniquesPiperidinesNeoplastic Stem CellsSignal TransductionCell Proliferation
Funding
- University of Michigan
- National Institutes of Health
- Medical School, University of Michigan
Citations
498
FWCI
11.56
field-weighted impact
References
49
Percentile
99%
vs. same field & year
Citations per year
References
ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome
Cell stem cell · 2007 · 3,968 citations
Piperine, a Major Constituent of Black Pepper, Inhibits Human P-glycoprotein and CYP3A4
Journal of Pharmacology and Experimental Therapeutics · 2002 · 524 citations
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
Genes & Development · 2003 · 2,396 citations
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