article Open AccessTop 1% cited
ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome
Cell stem cell · 2007 · Vol. 1(5) · pp. 555–567
Christophe Ginestier✉(University of Michigan–Ann Arbor)Min Hee Hur(Sungkyunkwan University)Emmanuelle Charafe‐Jauffret(Inserm)Florence Monville(Inserm)Julie Dutcher(University of Michigan–Ann Arbor)Marty Brown(University of Michigan–Ann Arbor)Jocelyne Jacquemier(Inserm)Patrice Viens(Inserm)Celina G. Kleer(University of Michigan–Ann Arbor)Suling Liu(University of Michigan–Ann Arbor)Anne F. Schott(University of Michigan–Ann Arbor)Daniel Hayes(University of Michigan–Ann Arbor)Daniel Birnbaum(Inserm)Max S. Wicha(University of Michigan–Ann Arbor)Gabriela Dontu(University of Michigan–Ann Arbor)
Cancer Cells and MetastasisEpigenetics and DNA MethylationCancer, Stress, Anesthesia, and Immune ResponseBiologyStem cellCancer stem cellProgenitor cellStem cell markerCancer researchImmunostainingAldehyde dehydrogenaseBreast cancerPathology
MeSH terms
Aldehyde Dehydrogenase 1 FamilyAldehyde DehydrogenaseAnimalsBreast NeoplasmsCell DifferentiationCell SeparationCells, CulturedFemaleFlow CytometryHumansImmunohistochemistryIsoenzymesPhenotypeNeoplastic Stem CellsBiomarkers
Funding
- OncoMed Pharmaceutical
- University of Michigan
- National Institutes of Health
- Medical School, University of Michigan
Citations
3,968
FWCI
58.24
field-weighted impact
References
49
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100%
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References
Families of retinoid dehydrogenases regulating vitamin A function
European Journal of Biochemistry · 2000 · 571 citations
Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells
Cancer Research · 2006 · 3,057 citations
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
Nature Medicine · 1997 · 6,906 citations
Identification of Pancreatic Cancer Stem Cells
Cancer Research · 2007 · 3,356 citations
Prospective identification of tumorigenic breast cancer cells
Proceedings of the National Academy of Sciences · 2003 · 10,327 citations
A Tumorigenic Subpopulation with Stem Cell Properties in Melanomas
Cancer Research · 2005 · 1,276 citations
Stem cells, cancer, and cancer stem cells
Nature · 2001 · 9,682 citations
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
Genes & Development · 2003 · 2,396 citations
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