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The Many Roles for Fluorine in Medicinal Chemistry

Journal of Medicinal Chemistry · 2008 · Vol. 51(15) · pp. 4359–4369
William K. Hagmann

Abstract

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTThe Many Roles for Fluorine in Medicinal ChemistryWilliam K. Hagmann†View Author Information Merck Research Laboratories, Rahway, New Jersey 07065† Contact information: phone, 732-594-7249; fax, 732-594-5966; e-mail, [email protected]Cite this: J. Med. Chem. 2008, 51, 15, 4359–4369Publication Date (Web):June 21, 2008Publication History Received29 February 2008Published online21 June 2008Published inissue 1 August 2008https://pubs.acs.org/doi/10.1021/jm800219fhttps://doi.org/10.1021/jm800219freview-articleACS PublicationsCopyright © 2008 American Chemical SocietyRequest reuse permissionsArticle Views33030Altmetric-Citations2988LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Amides,Fluorine,Inhibitors,Plasma,Trifluoromethyl Get e-Alerts

Fluorine in Organic ChemistryPharmacogenetics and Drug MetabolismSynthesis and Biological EvaluationCitationPhoneIconWorld Wide WebLibrary scienceComputer scienceSocial mediaChemistryPhilosophy

MeSH terms

AnimalsChemistry, PharmaceuticalEnzyme InhibitorsFluorineHumansProtein BindingStereoisomerismFluorine Compounds
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