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The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

Immunity · 2008 · Vol. 29(4) · pp. 538–550
Bo Zhong✉Yan YangShu LiYanyi WangYing LiFeici DiaoCao‐Qi LeiXiao HeLu ZhangPo TienHong-Bing Shu
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interferon and immune responsesRNA regulation and diseaseImmune Response and InflammationIRF3Signal transducing adaptor proteinBiologyCell biologyTranscription factorInterferon regulatory factorsMediatorInnate immune systemSignal transductionGene knockdown

MeSH terms

DEAD Box Protein 58STING ProteinAmino Acid SequenceCell LineCloning, MolecularHumansInterferon Type IIntracellular MembranesMembrane ProteinsMitochondriaMolecular Sequence DataPhosphorylationReceptors, ImmunologicTransfectionSignal Transduction
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References
Pathogen Recognition and Innate Immunity
Cell · 2006 · 11,743 citations
Type I Inteferon Gene Induction by the Interferon Regulatory Factor Family of Transcription Factors
Immunity · 2006 · 1,374 citations
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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
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