reviewTop 10% cited
Immune Escape Mechanisms as a Guide for Cancer Immunotherapy
Clinical Cancer Research · 2014 · Vol. 21(4) · pp. 687–692
Gregory L. Beatty✉(University of Pennsylvania)Whitney L. Gladney(University of Pennsylvania)
Abstract
Immunotherapy has demonstrated impressive outcomes for some patients with cancer. However, selecting patients who are most likely to respond to immunotherapy remains a clinical challenge. Here, we discuss immune escape mechanisms exploited by cancer and present strategies for applying this knowledge to improving the efficacy of cancer immunotherapy.
Cancer Immunotherapy and BiomarkersImmune Cell Function and InteractionImmunotherapy and Immune ResponsesImmunotherapyCancerCancer immunotherapyImmune systemMedicineImmune escapeImmunologyInternal medicine
MeSH terms
HumansImmunotherapyNeoplasmsTumor Escape
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