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Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets
Immunity · 1998 · Vol. 8(3) · pp. 275–283
Anne O’Garra✉(FX Palo Alto Laboratory)
T-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune ResponsesLymphokineBiologyImmune systemLymphotoxinImmunologyT helper cellAntigenT cellCytokineclone (Java method)
MeSH terms
Cell DifferentiationT-Lymphocytes, Helper-InducerT-Lymphocyte SubsetsCytokinesTh1 CellsTh2 CellsModels, Immunological
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References
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Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.
The Journal of Immunology · 1986 · 7,496 citations
Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells
Immunity · 1996 · 1,621 citations
Acquisition of Lymphokine-Producing Phenotype by CD4+ T Cells
Annual Review of Immunology · 1994 · 1,568 citations
Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity
Annual Review of Immunology · 1995 · 2,419 citations
INDUCTION OF TH1 AND TH2 CD4<sup>+</sup>T CELL RESPONSES:The Alternative Approaches
Annual Review of Immunology · 1997 · 1,466 citations
Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.
The Journal of Experimental Medicine · 1996 · 1,986 citations
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