articleTop 1% cited

SOST is a target gene for PTH in bone

Bone · 2005 · Vol. 37(2) · pp. 148–158

H. J. Keller✉(Novartis Institutes for BioMedical Research)Michaela Kneissel✉(Novartis (Switzerland))

Bone health and treatments Bone Metabolism and Diseases Bone health and osteoporosis researchSclerostinOsteocyteEndocrinologyInternal medicineCalvariaParathyroid hormoneBone mineralOsteoblastChemistryAnabolism

MeSH terms

Cyclic AMPAnimalsCell LineCycloheximideFemaleFemurColforsinGenetic MarkersGlycoproteinsOsteogenesisOvariectomyParathyroid HormonePeptide FragmentsProtein Synthesis InhibitorsRNA, Messenger

Citations

612

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10.88

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References

Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families

Endocrine Reviews · 1999 · 2,264 citations

Bone Dysplasia Sclerosteosis Results from Loss of the SOST Gene Product, a Novel Cystine Knot–Containing Protein

The American Journal of Human Genetics · 2001 · 1,008 citations

Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

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Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

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Human Molecular Genetics · 2001 · 1,146 citations

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

Proceedings of the National Academy of Sciences · 1998 · 4,244 citations

Sex Steroids and the Construction and Conservation of the Adult Skeleton

Endocrine Reviews · 2002 · 1,739 citations

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