articleTop 10% cited
Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDHhiCD44+ human breast cancer cells
Breast Cancer Research and Treatment · 2011 · Vol. 133(1) · pp. 75–87
Alysha K. Croker✉(Western University)Alison L. Allan(Western University)
Cancer Cells and MetastasisCancer, Hypoxia, and MetabolismCancer, Stress, Anesthesia, and Immune ResponseAldehyde dehydrogenaseBreast cancerCancer stem cellCancerChemotherapyCancer researchMedicineStem cellOncologyInternal medicine
MeSH terms
Aldehyde DehydrogenaseAntineoplastic AgentsBenzaldehydesBreast NeoplasmsCell SurvivalFemaleHumansRadiation ToleranceTretinoinBiomarkers, TumorNeoplastic Stem CellsHyaluronan ReceptorsDrug Resistance, NeoplasmCell Line, Tumor
Funding
- Canadian Institutes of Health Research
- Ontario Ministry of Research and Innovation
Citations
326
FWCI
9.72
field-weighted impact
References
47
Percentile
99%
vs. same field & year
Citations per year
References
Epithelial-Mesenchymal Transitions in Development and Disease
Cell · 2009 · 9,875 citations
Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells
Stem Cells · 2009 · 649 citations
Dissemination and growth of cancer cells in metastatic sites
Nature reviews. Cancer · 2002 · 3,915 citations
ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome
Cell stem cell · 2007 · 3,968 citations
Prospective identification of tumorigenic breast cancer cells
Proceedings of the National Academy of Sciences · 2003 · 10,327 citations
Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature
Cancer Research · 2009 · 1,165 citations
Notch Promotes Radioresistance of Glioma Stem Cells
Stem Cells · 2009 · 634 citations
Cancer Statistics, 2010
CA A Cancer Journal for Clinicians · 2010 · 12,602 citations
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