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5-Arylidene-2-imino-4-thiazolidinones: Design and synthesis of novel anti-inflammatory agents

Bioorganic & Medicinal Chemistry · 2005 · Vol. 13(13) · pp. 4243–4252
Rosaria OttanàRosanna MaccariMaria Letizia BarrecaGiuseppe BrunòArchimede RotondoAntonietta RossiGiuseppa ChiricostaRosanna Di PaolaLidia SautebinSalvatore CuzzocreaMaria Gabriella Vigorita
Inflammatory mediators and NSAID effectsSynthesis and biological activitySynthesis and Reactions of Organic CompoundsChemistryCarrageenanMoietyPharmacologyGene isoformEdemaStereochemistryInflammationAnti-inflammatoryStructure–activity relationship

MeSH terms

AnimalsAnti-Inflammatory Agents, Non-SteroidalBinding SitesCarrageenanEdemaInflammationMacrophagesMaleMonocytesPeroxidasePleurisyProstaglandin-Endoperoxide SynthasesStructure-Activity RelationshipDrug DesignCyclooxygenase Inhibitors
Citations
283
FWCI
5.27
field-weighted impact
References
25
Percentile
96%
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Citations per year
References
The PyMOL Molecular Graphics System
Medical Entomology and Zoology · 2002 · 18,132 citations
Cyclooxygenase in biology and disease
The FASEB Journal · 1998 · 2,501 citations
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