article Open AccessTop 1% cited
Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum—The η-carbonic anhydrases
Bioorganic & Medicinal Chemistry Letters · 2014 · Vol. 24(18) · pp. 4389–4396
Sonia Del Prete(Institute of Biosciences and Bioresources)Daniela Vullo(University of Florence)Gillian M. Fisher(Griffith University)Katherine T. Andrews(Griffith University)Sally‐Ann Poulsen(Griffith University)Clemente Capasso✉(Institute of Biosciences and Bioresources)Claudiu T. Supuran✉(University of Florence)
Enzyme function and inhibitionSynthesis and Catalytic ReactionsCholinesterase and Neurodegenerative DiseasesCarbonic anhydrasePlasmodium falciparumChemistrySulfamideBiochemistryProtozoaMalariaEnzymeGenePlasmodium (life cycle)
MeSH terms
Amino Acid SequenceCarbonic AnhydrasesCarbonic Anhydrase InhibitorsDose-Response Relationship, DrugHumansIsoenzymesMolecular Sequence DataOrganometallic CompoundsPhylogenyPlasmodium falciparumStructure-Activity RelationshipZincMolecular StructureSequence AlignmentDrug Discovery
Funding
- Medical Research Council
- Australian Research Council
- National Health and Medical Research Council
Citations
321
FWCI
18.93
field-weighted impact
References
79
Percentile
100%
vs. same field & year
Citations per year
Cited by
Structure and function of carbonic anhydrases
Biochemical Journal · 2016 · 888 citations
References
Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
Nature Reviews Drug Discovery · 2008 · 3,109 citations
Interfering with pH regulation in tumours as a therapeutic strategy
Nature Reviews Drug Discovery · 2011 · 1,519 citations
Carbonic anhydrase inhibitors
Bioorganic & Medicinal Chemistry Letters · 2010 · 610 citations
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