article Open AccessTop 1% cited
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining
Nature Structural & Molecular Biology · 2010 · Vol. 17(9) · pp. 1144–1151
Kyle M. Miller✉(University of Cambridge)Jorrit Tjeertes(Wellcome/Cancer Research UK Gurdon Institute)Julia Coates(Wellcome/Cancer Research UK Gurdon Institute)Gaëlle Legube(Université de Toulouse)Sophie E. Polo(Wellcome/Cancer Research UK Gurdon Institute)Sébastien Britton(Wellcome/Cancer Research UK Gurdon Institute)Stephen P. Jackson(University of Cambridge)
Histone Deacetylase Inhibitors ResearchDNA Repair MechanismsEpigenetics and DNA MethylationChromatinDNA damageHistone deacetylase 2HistoneBiologyDNA repairCell biologyHDAC1DNAHistone deacetylase
MeSH terms
DNA RepairHistonesHumansRNA, Small InterferingCell Line, TumorDNA Breaks, Double-StrandedHistone Deacetylase 1Histone Deacetylase 2
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Cited by
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks
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References
Histone deacetylases and cancer
Oncogene · 2007 · 1,039 citations
The DNA Damage Response: Ten Years After
Molecular Cell · 2007 · 1,666 citations
Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
Cell · 1997 · 5,018 citations
Chromatin Modifications and Their Function
Cell · 2007 · 10,677 citations
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