article Open AccessTop 1% cited
Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease
Neuron · 2007 · Vol. 55(5) · pp. 697–711
Jorge J. Palop✉(Gladstone Institutes)Jeannie Chin(Gladstone Institutes)Erik D. Roberson(University of California, San Francisco)Jun Wang(University of California, San Francisco)Myo T. Thwin(Gladstone Institutes)Nga Bien‐Ly(Gladstone Institutes)Jong W. Yoo(Baylor College of Medicine)Kaitlyn O. Ho(Gladstone Institutes)Gui-Qiu Yu(Gladstone Institutes)Anatol C. Kreitzer(Gladstone Institutes)Steven Finkbeiner(University of California, San Francisco)Jeffrey L. Noebels(Baylor College of Medicine)Lennart Mucke✉(University of California, San Francisco)
Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology ResearchMemory and Neural MechanismsNeuroscienceExcitatory postsynaptic potentialHippocampal formationInhibitory postsynaptic potentialNeuronal circuitsPremovement neuronal activityBiological neural networkHippocampusAlzheimer's diseaseBiology
MeSH terms
Alzheimer DiseaseAnimalsCognition DisordersDisease Models, AnimalEpilepsygamma-Aminobutyric AcidHumansMice, TransgenicNeural InhibitionNeural PathwaysSynaptic TransmissionNeuronal PlasticityNeurotoxinsAmyloid beta-PeptidesAmyloid beta-Protein Precursor
Funding
- Foundation for the National Institutes of Health
Citations
1,667
FWCI
24.47
field-weighted impact
References
91
Percentile
100%
vs. same field & year
Citations per year
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References
High-Level Neuronal Expression of Aβ<sub>1–42</sub>in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation
Journal of Neuroscience · 2000 · 1,860 citations
The Human Hippocampus and Spatial and Episodic Memory
Neuron · 2002 · 2,416 citations
Regulation of NMDA receptor trafficking by amyloid-β
Nature Neuroscience · 2005 · 1,544 citations
Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway
Journal of Neuroscience · 2007 · 1,574 citations
Incidence and Predictors of Seizures in Patients with Alzheimer's Disease
Epilepsia · 2006 · 592 citations
The organization of recent and remote memories
Nature reviews. Neuroscience · 2005 · 2,101 citations
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
Biochemical and Biophysical Research Communications · 1984 · 5,345 citations
Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy
Brain Research · 1989 · 929 citations
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