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Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis
Journal of Allergy and Clinical Immunology · 2012 · Vol. 130(6) · pp. 1344–1354
Julia Gittler✉(Rockefeller University)Avner Shemer(Tel Aviv University)Mayte Suárez‐Fariñas(Rockefeller University)Judilyn Fuentes‐Duculan(Rockefeller University)Kara J. Gulewicz(Washington University in St. Louis)Claire Q. Wang(Rockefeller University)Hiroshi Mitsui(Rockefeller University)Irma Cardinale(Rockefeller University)Cristina de Guzman Strong(Washington University in St. Louis)James G. Krueger(Rockefeller University)Emma Guttman‐Yassky(Rockefeller University)
Dermatology and Skin DiseasesAsthma and respiratory diseasesAllergic Rhinitis and SensitizationS100A9S100A8ImmunologyAtopic dermatitisPathogenesisMedicineDiseaseCytokineImmune systemInflammation
MeSH terms
S100 Calcium Binding Protein A7Interleukin-22Acute DiseaseAdultAgedChronic DiseaseDermatitis, AtopicFemaleHumansInterleukinsMaleMiddle AgedS100 ProteinsSkinUp-Regulation
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References
Possible Pathogenic Role of Th17 Cells for Atopic Dermatitis
Journal of Investigative Dermatology · 2008 · 665 citations
Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways
British Journal of Dermatology · 2008 · 796 citations
Cytokine modulation of atopic dermatitis filaggrin skin expression
Journal of Allergy and Clinical Immunology · 2007 · 1,080 citations
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis
Nature Genetics · 2006 · 2,920 citations
Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis
Journal of Investigative Dermatology · 2010 · 655 citations
Atopic dermatitis and the atopic march
Journal of Allergy and Clinical Immunology · 2003 · 1,210 citations
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
The Journal of Experimental Medicine · 2006 · 2,281 citations
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