reviewTop 1% cited
Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response
Molecular Psychiatry · 2004 · Vol. 9(5) · pp. 442–473
Julia Kirchheiner✉(Charité - Universitätsmedizin Berlin)Katharina Nickchen(Charité - Universitätsmedizin Berlin)Miroslav Bauer(Charité - Universitätsmedizin Berlin)Ma‐Li Wong(University of California, Los Angeles)Julio Licínio(University of California, Los Angeles)I Roots(Charité - Universitätsmedizin Berlin)J. Brockmöller(University of Göttingen)
Pharmacogenetics and Drug MetabolismReceptor Mechanisms and SignalingNeurotransmitter Receptor Influence on BehaviorPharmacogeneticsCYP2D6PharmacogenomicsCYP2C19AntipsychoticPharmacologyMedicinePharmacodynamicsAdverse effectDrug
MeSH terms
AllelesAntidepressive AgentsAryl Hydrocarbon HydroxylasesCarrier ProteinsCytochromesDopamineDose-Response Relationship, DrugDrug ResistanceEpistasis, GeneticGenotypeHumansMixed Function OxygenasesInactivation, MetabolicNorepinephrinePhenotype
Citations
722
FWCI
50.75
field-weighted impact
References
319
Percentile
100%
vs. same field & year
Citations per year
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References
The serotonin syndrome
American Journal of Psychiatry · 1991 · 1,341 citations
Functional significance of a C→A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine
British Journal of Clinical Pharmacology · 1999 · 746 citations
Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugs
British Journal of Clinical Pharmacology · 2002 · 578 citations
Allelic Variation of Human Serotonin Transporter Gene Expression
Journal of Neurochemistry · 1996 · 2,220 citations
Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
Molecular Psychiatry · 1998 · 615 citations
The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers
Molecular Psychiatry · 1998 · 676 citations
Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors
The British Journal of Psychiatry · 2001 · 805 citations
Serotonin transporter gene polymorphism and antidepressant response
Neuroreport · 2000 · 402 citations
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