review Open AccessTop 1% cited
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
Biological Psychiatry · 2009 · Vol. 65(9) · pp. 732–741
Andrew H. Miller✉(Emory University)Vladimir Maletic(University of South Carolina)Charles L. Raison(Emory University)
Tryptophan and brain disordersStress Responses and CortisolNeuroendocrine regulation and behaviorProinflammatory cytokineAntidepressantInflammationMedicineMood disordersNeurochemicalMajor depressive disorderExcitotoxicityImmune dysregulationGlutamate receptor
MeSH terms
AnimalsAnti-Inflammatory AgentsBasal GangliaBrainMajor Depressive DisorderDepressive Disorder, MajorHumansInflammationNeuronal PlasticityNeurosecretory SystemsStress, PsychologicalBiomarkersCytokinesNeurotransmitter Agents
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Molecular Psychiatry · 2006 · 791 citations
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice
Molecular Psychiatry · 2008 · 1,258 citations
The Proinflammatory Cytokines Interleukin-1beta and Tumor Necrosis Factor-Alpha Activate Serotonin Transporters
Neuropsychopharmacology · 2006 · 540 citations
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