article Open AccessTop 1% cited
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
Immunity · 2014 · Vol. 41(5) · pp. 843–852
Liufu Deng(University of Chicago)Hua Liang(University of Chicago)Meng Xu(University of Chicago)Xuanming Yang(University of Chicago)Byron Burnette(University of Chicago)Ainhoa Arina(University of Chicago)Xiao-Dong Li(The University of Texas Southwestern Medical Center)Helena J. Mauceri(University of Chicago)Michael A. Beckett(University of Chicago)Thomas E. Darga(University of Chicago)Xiaona Huang(University of Chicago)Thomas F. Gajewski(University of Chicago)Zhijian J. Chen(Howard Hughes Medical Institute)Yang‐Xin Fu✉(University of Chicago)Ralph R. Weichselbaum✉(University of Chicago)
interferon and immune responsesViral Infections and VectorsInflammasome and immune disordersBiologyImmunityInterferonCancer researchDNAStingCytosolInterferon type IVirologyImmunology
MeSH terms
STING ProteinCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseAnimalsAntineoplastic AgentsCells, CulturedDendritic CellsDNAImmunity, InnateMembrane ProteinsMice, Inbred C57BLNeoplasmsNucleotides, CyclicNucleotidyltransferasesRadiation, IonizingSignal Transduction
Funding
- National Institutes of Health
Citations
2,009
FWCI
30.77
field-weighted impact
References
43
Percentile
100%
vs. same field & year
Citations per year
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References
Pattern Recognition Receptors and Inflammation
Cell · 2010 · 8,539 citations
Sterile inflammation: sensing and reacting to damage
Nature reviews. Immunology · 2010 · 2,919 citations
Irradiation and anti–PD-L1 treatment synergistically promote antitumor immunity in mice
Journal of Clinical Investigation · 2014 · 2,059 citations
Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
Nature Medicine · 2007 · 2,933 citations
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