review Open AccessTop 1% cited
The cGAS–STING pathway as a therapeutic target in inflammatory diseases
Nature reviews. Immunology · 2021 · Vol. 21(9) · pp. 548–569
Alexiane Decout✉(École Polytechnique Fédérale de Lausanne)Jason D. Katz(Ifm Therapeutics (United States))Shankar Venkatraman(Ifm Therapeutics (United States))Andrea Ablasser(École Polytechnique Fédérale de Lausanne)
interferon and immune responsesViral Infections and VectorsInflammasome and immune disordersStingInnate immune systemInflammationStimulator of interferon genesBiologySignal transductionMediatorImmune systemCell biologyImmunology
MeSH terms
DNA, MitochondrialGain of Function MutationAnimalsAutophagyEnzyme InhibitorsHumansInflammationMembrane ProteinsModels, BiologicalModels, MolecularNucleotides, CyclicNucleotidyltransferasesSignal TransductionCell DeathInflammation Mediators
Funding
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Citations
2,056
FWCI
106.40
field-weighted impact
References
217
Percentile
100%
vs. same field & year
Citations per year
Cited by
The interaction between ferroptosis and inflammatory signaling pathways
Cell Death and Disease · 2023 · 451 citations
References
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
Immunity · 2014 · 2,009 citations
The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
Cell Reports · 2013 · 739 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.