reviewTop 1% cited

The mechanisms of drug release in poly(lactic-co-glycolic acid)-based drug delivery systems—A review

International Journal of Pharmaceutics · 2011 · Vol. 415(1-2) · pp. 34–52

Susanne Fredenberg✉(Lund University)Marie Wahlgren(Lund University)Mats Reslow(Novo Nordisk (Denmark))Anders Axelsson(Lund University)

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Advanced Drug Delivery Systems Drug Solubulity and Delivery Systems Nanoparticle-Based Drug DeliveryGlycolic acidDrugDrug deliveryPharmacologyLactic acidChemistryMedicineOrganic chemistryBacteriaBiology

MeSH terms

Polylactic Acid-Polyglycolic Acid CopolymerDelayed-Action PreparationsDrug CarriersHumansModels, ChemicalPolyglycolic AcidSolubilityLactic AcidChemical Phenomena

Citations

1,224

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27.81

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References

Visual Evidence of Acidic Environment Within Degrading Poly(lactic-co-glycolic acid) (PLGA) Microspheres

Pharmaceutical Research · 2000 · 745 citations

Controlled Delivery Systems for Proteins Based on Poly(Lactic/Glycolic Acid) Microspheres

Pharmaceutical Research · 1991 · 845 citations

Nano/micro technologies for delivering macromolecular therapeutics using poly(d,l-lactide-co-glycolide) and its derivatives

Journal of Controlled Release · 2007 · 1,012 citations

Delivery of Therapeutic Proteins

Journal of Pharmaceutical Sciences · 2010 · 527 citations

Mathematical modeling of drug delivery

International Journal of Pharmaceutics · 2008 · 1,288 citations

Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles

International Journal of Pharmaceutics · 2008 · 776 citations

On the importance and mechanisms of burst release in matrix-controlled drug delivery systems

Journal of Controlled Release · 2001 · 1,737 citations

Biodegradation and biocompatibility of PLA and PLGA microspheres

Advanced Drug Delivery Reviews · 1997 · 2,576 citations

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