article Open AccessTop 1% cited
The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis
Neuron · 2003 · Vol. 37(4) · pp. 649–661
Michael A. Cowley✉(Vollum Institute)Roy G. Smith(Baylor College of Medicine)Sabrina Diano(Yale University)Matthias H. Tschöp(Eli Lilly (United States))Nina Pronchuk(University of Alberta)Kevin L. Grove(Oregon National Primate Research Center)Christian J. StrasburgerMartin BidlingmaierMichael Esterman(Eli Lilly (United States))Mark L. Heiman(Eli Lilly (United States))Luis Miguel García‐Segura(Consejo Superior de Investigaciones Científicas)Eduardo A. Nillni(Rhode Island Hospital)Pablo Méndez(Consejo Superior de Investigaciones Científicas)Malcolm J. Low(Oregon Health & Science University)Péter Sótonyi(Yale University)Jeffrey M. Friedman(Rockefeller University)Hongyan Liu(Rockefeller University)Shirly Pinto(Rockefeller University)William F. Colmers(University of Alberta)Roger D. Cone(Oregon Health & Science University)Tamás L. Horváth(Yale University)
Regulation of Appetite and ObesityBiochemical Analysis and Sensing TechniquesAdipose Tissue and MetabolismGhrelinEnergy homeostasisMechanism (biology)NeuroscienceHomeostasisHypothalamusAction (physics)Mechanism of actionBiologyCell biology
MeSH terms
AnimalsCentral Nervous SystemCorticotropin-Releasing HormoneEnergy MetabolismFemaleHomeostasisHypothalamusLuminescent ProteinsMice, TransgenicNerve NetNeuronsNeuropeptide YOrgan SpecificityParaventricular Hypothalamic NucleusPro-Opiomelanocortin
Funding
- Merck
- National Institutes of Health
- Canadian Institutes of Health Research
Citations
1,661
FWCI
31.98
field-weighted impact
References
68
Percentile
100%
vs. same field & year
Citations per year
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References
Ghrelin, a Novel Growth Hormone-Releasing Acylated Peptide, Is Synthesized in a Distinct Endocrine Cell Type in the Gastrointestinal Tracts of Rats and Humans<sup>1</sup>
Endocrinology · 2000 · 1,801 citations
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Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior
Cell · 1998 · 5,481 citations
The anatomy of neuropeptide-y-containing neurons in rat brain
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Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight*
Endocrine Reviews · 1999 · 1,459 citations
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Diabetes · 2001 · 1,114 citations
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