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Long‐term outcome and mortality after transsphenoidal adenomectomy for acromegaly

Clinical Endocrinology · 2003 · Vol. 58(1) · pp. 86–91

Catherine BeauregardUyen TruongJules Hardy(Université de Montréal)Omar Serri✉

Abstract

Our observations confirm that uncontrolled acromegaly increases mortality compared to the general population and that mortality rates similar to the general population are restored once remission is induced.

Pituitary Gland Disorders and Treatments Growth Hormone and Insulin-like Growth Factors Adrenal and Paraganglionic TumorsAcromegalyMedicineTranssphenoidal surgeryPerioperativePopulationMortality rateRetrospective cohort studySurgeryInternal medicineOctreotide

MeSH terms

AcromegalyAdenomaAdolescentAdultAgedCause of DeathCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedPituitary NeoplasmsRemission InductionRetrospective Studies

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299

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A meta-analysis of the effect of lowering serum levels of GH and IGF-I on mortality in acromegaly