article Open AccessTop 1% cited
Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development
Cell stem cell · 2008 · Vol. 3(2) · pp. 169–181
Akio Kobayashi✉(Harvard University)M. Todd Valerius(Harvard University)Joshua W. Mugford(Harvard University)Thomas J. Carroll(Harvard University)Michelle Self(St. Jude Children's Research Hospital)Guillermo Oliver(St. Jude Children's Research Hospital)Andrew P. McMahon(Harvard University)
Renal and related cancersRenal cell carcinoma treatmentGenetic and Kidney Cyst DiseasesNephronBiologyProgenitor cellMesenchymePopulationProgenitorMultipotent Stem CellCell biologyKidney developmentIngression
MeSH terms
AnimalsCell DifferentiationChimeraImmunohistochemistryKidneyMice, Inbred C57BLMice, TransgenicNephronsTranscription FactorsTranscriptional ActivationHomeodomain ProteinsMicroscopy, ConfocalOrganogenesisWnt ProteinsMice
Citations
962
FWCI
15.45
field-weighted impact
References
46
Percentile
99%
vs. same field & year
Citations per year
Cited by
Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells
Cell stem cell · 2013 · 851 citations
Patterning a Complex Organ: Branching Morphogenesis and Nephron Segmentation in Kidney Development
Developmental Cell · 2010 · 708 citations
Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis
American Journal Of Pathology · 2009 · 1,398 citations
References
Generalized lacZ expression with the ROSA26 Cre reporter strain
Nature Genetics · 1999 · 4,871 citations
Distinct roles for Hedgehog and canonical Wnt signaling in specification,differentiation and maintenance of osteoblast progenitors
Development · 2006 · 1,001 citations
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
Current Biology · 1998 · 1,301 citations
A Highly Efficient Escherichia coli-Based Chromosome Engineering System Adapted for Recombinogenic Targeting and Subcloning of BAC DNA
Genomics · 2001 · 1,191 citations
Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.
Genes & Development · 1991 · 1,379 citations
Intrinsic Epithelial Cells Repair the Kidney after Injury
Cell stem cell · 2008 · 861 citations
Wnt9b Plays a Central Role in the Regulation of Mesenchymal to Epithelial Transitions Underlying Organogenesis of the Mammalian Urogenital System
Developmental Cell · 2005 · 897 citations
Regulation of Cre Recombinase Activity by Mutated Estrogen Receptor Ligand-Binding Domains
Biochemical and Biophysical Research Communications · 1997 · 995 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.