articleTop 10% cited
Regulation of Akt and glycogen synthase kinase-3β phosphorylation by sodium valproate and lithium
Neuropharmacology · 2002 · Vol. 43(7) · pp. 1158–1164
Patrizia De Sarno(University of Alabama at Birmingham)Xiaohua Li(University of Alabama at Birmingham)Richard S. Jope✉(University of Alabama at Birmingham)
Genetics and Neurodevelopmental DisordersNuclear Receptors and SignalingBipolar Disorder and TreatmentProtein kinase BPhosphorylationGSK-3Lithium (medication)Histone deacetylaseHistone deacetylase inhibitorGSK3BGlycogen synthaseChemistryPI3K/AKT/mTOR pathway
MeSH terms
Glycogen Synthase Kinase 3 betaAnimalsBrainEnzyme InhibitorsHumansMaleMice, Inbred C57BLPhosphorylationProto-Oncogene ProteinsTumor Cells, CulturedValproic AcidProtein Serine-Threonine KinasesLithium ChlorideGlycogen Synthase Kinase 3Proto-Oncogene Proteins c-akt
Funding
- National Institutes of Health
Citations
433
FWCI
9.31
field-weighted impact
References
27
Percentile
98%
vs. same field & year
Citations per year
Cited by
GSK-3: tricks of the trade for a multi-tasking kinase
Journal of Cell Science · 2003 · 2,066 citations
References
Mechanism of activation of protein kinase B by insulin and IGF-1.
The EMBO Journal · 1996 · 3,023 citations
Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells
Current Biology · 1996 · 1,319 citations
Ten years of protein kinase B signalling: a hard Akt to follow
Trends in Biochemical Sciences · 2001 · 1,178 citations
Specificity and mechanism of action of some commonly used protein kinase inhibitors
Biochemical Journal · 2000 · 4,060 citations
Transcription-dependent and -independent control of neuronal survival by the PI3K–Akt signaling pathway
Current Opinion in Neurobiology · 2001 · 1,181 citations
A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding
Analytical Biochemistry · 1976 · 225,297 citations
Cellular survival: a play in three Akts
Genes & Development · 1999 · 4,218 citations
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
Analytical Biochemistry · 1976 · 209,807 citations
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