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Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

Nature Nanotechnology · 2013 · Vol. 8(10) · pp. 772–781
Stefan TenzerDominic DocterJörg KuharevAnna MusyanovychVerena FetzRouven HechtFlorian SchlenkDagmar FischerKlytaimnistra KiouptsiChristoph ReinhardtKatharina LandfesterHansjörg SchildMichael MaskosShirley K. KnauerRoland H. Stauber
Nanoparticle-Based Drug DeliveryProtein Interaction Studies and Fluorescence AnalysisPolymer Surface Interaction StudiesNanoparticleSurface modificationBiophysicsNanotoxicologyBiological fluidsNanotechnologyProteomicsChemistryCorona (planetary geology)Nanobiotechnology

MeSH terms

Blood PlateletsBlood ProteinsCell LineHumansParticle SizePolystyrenesSilicon DioxideCell DeathMicroscopy, ConfocalComputational BiologyEndothelial CellsNanoparticlesMicrovessels

Funding

  • Deutsche Forschungsgemeinschaft
  • Bundesministerium für Bildung und Forschung
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