article Open AccessTop 1% cited
Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface
Nature Nanotechnology · 2013 · Vol. 8(2) · pp. 137–143
Anna Salvati✉(University College Dublin)Andrzej S. Pitek(University College Dublin)Marco P. Monopoli(University College Dublin)Kanlaya Prapainop(University College Dublin)Francesca Baldelli Bombelli(University College Dublin)Delyan R. Hristov(University College Dublin)Philip M. Kelly(University College Dublin)Christoffer Åberg(University College Dublin)Eugene Mahon(University College Dublin)Kenneth A. Dawson(University College Dublin)
Nanoparticle-Based Drug DeliveryRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesTransferrinBiomoleculeTransferrin receptorNanoparticleReceptorNanotechnologyBiophysicsChemistryNanomedicineNanomaterials
MeSH terms
AdsorptionAnimalsAntibodiesCircular DichroismEpithelial CellsFlow CytometryHumansParticle SizeProteinsReceptors, TransferrinSilicon DioxideTransferrinRNA, Small InterferingCell Line, TumorMice
Funding
- European Commission
- Irish Research Council for Science, Engineering and Technology
- Science Foundation Ireland
- University College Dublin
- Irish Research Council
- European Social Fund
Citations
1,789
FWCI
83.62
field-weighted impact
References
36
Percentile
100%
vs. same field & year
Citations per year
Cited by
Surface Modifications of Nanoparticles for Stability in Biological Fluids
Materials · 2018 · 532 citations
Effect of polyethyleneglycol (PEG) chain length on the bio–nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake in cancer cells
Nanoscale · 2013 · 563 citations
Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology
Nature Nanotechnology · 2013 · 2,144 citations
Insight into nanoparticle cellular uptake and intracellular targeting
Journal of Controlled Release · 2014 · 756 citations
Biomolecular coronas provide the biological identity of nanosized materials
Nature Nanotechnology · 2012 · 2,677 citations
Principles of nanoparticle design for overcoming biological barriers to drug delivery
Nature Biotechnology · 2015 · 6,477 citations
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
Advanced Drug Delivery Reviews · 2013 · 2,726 citations
Cancer nanomedicine: progress, challenges and opportunities
Nature reviews. Cancer · 2016 · 5,494 citations
References
Strategies in the design of nanoparticles for therapeutic applications
Nature Reviews Drug Discovery · 2010 · 3,576 citations
Cancer nanotechnology: opportunities and challenges
Nature reviews. Cancer · 2005 · 4,505 citations
PEGylated nanoparticles for biological and pharmaceutical applications
Advanced Drug Delivery Reviews · 2003 · 1,572 citations
Size and shape effects in the biodistribution of intravascularly injected particles
Journal of Controlled Release · 2009 · 934 citations
Nanomedicine: current status and future prospects
The FASEB Journal · 2005 · 1,986 citations
Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile
Science Translational Medicine · 2012 · 1,113 citations
Understanding biophysicochemical interactions at the nano–bio interface
Nature Materials · 2009 · 6,869 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.