reviewTop 1% cited
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
Nature Genetics · 2003 · Vol. 33(S3) · pp. 245–254
Rudolf Jaenisch✉(Massachusetts Institute of Technology)Adrian Bird(University of Edinburgh)
Epigenetics and DNA MethylationGenetics and Neurodevelopmental DisordersCancer-related gene regulationEpigeneticsBiologyDNA methylationMulticellular organismEpigenetic regulation of neurogenesisEpigenetics of physical exerciseHistoneGeneticsGeneRegulation of gene expression
MeSH terms
AgingAnimalsDietDosage Compensation, GeneticHumansModels, GeneticMutationNeoplasmsPhenotypeSignal TransductionGenomeGenomic ImprintingGene Expression Regulation, DevelopmentalDNA MethylationCloning, Organism
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References
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
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The fundamental role of epigenetic events in cancer
Nature Reviews Genetics · 2002 · 5,646 citations
Cancer-epigenetics comes of age
Nature Genetics · 1999 · 2,354 citations
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
Nature Genetics · 1999 · 4,983 citations
Active demethylation of the paternal genome in the mouse zygote
Current Biology · 2000 · 959 citations
CpG islands as gene markers in the human genome
Genomics · 1992 · 916 citations
Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours
The Journal of Pathology · 2001 · 748 citations
CpG islands as gene markers in the vertebrate nucleus
Trends in Genetics · 1987 · 685 citations
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