reviewTop 1% cited
The fundamental role of epigenetic events in cancer
Nature Reviews Genetics · 2002 · Vol. 3(6) · pp. 415–428
Peter A. Jones✉(University of Southern California)Stephen B. Baylin(Sidney Kimmel Comprehensive Cancer Center)
Epigenetics and DNA MethylationCancer-related gene regulationGenomics and Chromatin DynamicsEpigeneticsBiologyDNA methylationChromatinCancer epigeneticsEpigenetics of physical exerciseGeneticsGene silencingChromatin remodelingEpigenomics
MeSH terms
Chromosome MappingHumansMass ScreeningNeoplasmsSignal TransductionGenome, HumanDNA Methylation
Funding
- National Institutes of Health
- National Cancer Institute
- National Institute of Environmental Health Sciences
Citations
5,646
FWCI
79.90
field-weighted impact
References
113
Percentile
100%
vs. same field & year
Citations per year
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References
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Cancer-epigenetics comes of age
Nature Genetics · 1999 · 2,354 citations
The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion
Molecular Cell · 2001 · 1,374 citations
DNA hypermethylation in tumorigenesis: epigenetics joins genetics
Trends in Genetics · 2000 · 1,634 citations
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
Cell · 1999 · 6,039 citations
Histone acetylation and transcriptional regulatory mechanisms
Genes & Development · 1998 · 1,819 citations
DNA methylation patterns and epigenetic memory
Genes & Development · 2002 · 7,054 citations
Gene expression profiling predicts clinical outcome of breast cancer
Nature · 2002 · 9,574 citations
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