articleTop 10% cited
An auxin-based degron system for the rapid depletion of proteins in nonplant cells
Nature Methods · 2009 · Vol. 6(12) · pp. 917–922
Kohei Nishimura✉(Osaka University)Tatsuo Fukagawa(National Institute of Genetics)Haruhiko Takisawa(Osaka University)Tatsuo Kakimoto(Osaka University)Masato T. Kanemaki(Osaka University)
Protein Degradation and InhibitorsUbiquitin and proteasome pathwaysPlant Virus Research StudiesDegronAuxinUbiquitin ligaseCell biologyBiologyMutantTranscription factorRepressorUbiquitinF-box protein
MeSH terms
AnimalsCell LineChickensIndoleacetic AcidsProteinsSaccharomyces cerevisiaeSKP Cullin F-Box Protein LigasesGreen Fluorescent Proteins
Citations
1,817
FWCI
6.99
field-weighted impact
References
36
Percentile
98%
vs. same field & year
Citations per year
Cited by
Fluorescent fusion protein knockout mediated by anti-GFP nanobody
Nature Structural & Molecular Biology · 2011 · 554 citations
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks
Nature Structural & Molecular Biology · 2014 · 661 citations
Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors
Cell Reports · 2016 · 752 citations
References
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
Nature · 2001 · 9,337 citations
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
Proceedings of the National Academy of Sciences · 1992 · 4,950 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
