articleTop 1% cited
Prospective Long‐Term Study of Vagus Nerve Stimulation for the Treatment of Refractory Seizures
Epilepsia · 2000 · Vol. 41(9) · pp. 1195–1200
Christopher M. DeGiorgio✉(Olive View-UCLA Medical Center)Steven C. Schachter(Beth Israel Deaconess Medical Center)Adrian HandforthMartin Salinsky(Oregon Health & Science University)Jason D. ThompsonBasim M. Uthman(University of Florida)Ronald C. Reed(Southern Illinois University School of Medicine)Sprenker Collin(University Hospitals of Cleveland)Evelyn S. Tecoma(University of California, San Diego)George L. Morris(Medical College of Wisconsin)Bradley V. Vaughn(University of North Carolina at Chapel Hill)Dean K. Naritoku(Southern Illinois University School of Medicine)Thomas R. Henry(Case Western Reserve University)Douglas Labar(Olive View-UCLA Medical Center)R. C. Gilmartin(PRN of Kansas)David M. Labiner(Cornell University)Ivan Osorio(University of Kansas)R. Ristanovic(University of Arizona)J. Jones(University of Wisconsin–Madison)J. V. Murphy(Children's Mercy Hospital)G. C. Ney(Jewish Hospital)James W. WhelessPaul B. LewisChristi Heck(West Los Angeles College)
Abstract
The efficacy of VNS improves during 12 months, and many subjects sustain >75% reductions in seizures.
Vagus Nerve Stimulation ResearchEEG and Brain-Computer InterfacesNeuroscience and Neural EngineeringVagus nerve stimulationEpilepsyMedicineRefractory (planetary science)StimulationAnesthesiaRandomized controlled trialProspective cohort studyClinical trialSurgery
MeSH terms
Electric Stimulation TherapyEpilepsyHumansLongitudinal StudiesProspective StudiesVagus NerveTreatment Outcome
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Cited by
Two‐year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial
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Vagus Nerve Stimulation (VNS™) for Treatment-Resistant Depression Efficacy, Side Effects, and Predictors of Outcome
Neuropsychopharmacology · 2001 · 571 citations
References
Locus Coeruleus Lesions Suppress the Seizure‐Attenuating Effects of Vagus Nerve Stimulation
Epilepsia · 1998 · 554 citations
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