review Open AccessTop 1% cited
Review article: the role of butyrate on colonic function
Alimentary Pharmacology & Therapeutics · 2007 · Vol. 27(2) · pp. 104–119
Henrike M. Hamer✉(TiFN)Daisy Jonkers(TiFN)Koen Venema(Pension Fund for Care and Well-Being)Steven Vanhoutvin(TiFN)Freddy J. Troost(TiFN)Robert J. Brummer(Maastricht University)
Abstract
Although most studies point towards beneficial effects of butyrate, more human in vivo studies are needed to contribute to our current understanding of butyrate-mediated effects on colonic function in health and disease.
Food composition and propertiesDiet and metabolism studiesDigestive system and related healthButyrateShort-chain fatty acidOxidative stressBarrier functionCarcinogenesisInflammationMedicineCancer researchPharmacologyBiochemistry
MeSH terms
AnimalsButyratesChild, PreschoolColonColonic NeoplasmsDietary FiberEnemaFatty Acids, VolatileHumansInfant, NewbornInflammationIntestinal MucosaRabbitsSatiationOxidative Stress
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References
Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides
Physiological Reviews · 2001 · 3,020 citations
Energy contributions of volatile fatty acids from the gastrointestinal tract in various species
Physiological Reviews · 1990 · 2,659 citations
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Oxidative Stress and Pathogenesis of Inflammatory Bowel Disease: An Epiphenomenon or the Cause?
Digestive Diseases and Sciences · 2007 · 581 citations
The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids
Journal of Biological Chemistry · 2003 · 2,311 citations
Epidemiology of cancer of the colon and rectum
Cancer · 1971 · 1,342 citations
Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine
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