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Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury

Cell stem cell · 2015 · Vol. 17(3) · pp. 329–340
Enric Llorens-BobadillaSheng ZhaoAvni BaserGonzalo Saiz-CastroKlara ZwadloAna Martín-Villalba
Neurogenesis and neuroplasticity mechanismsSingle-cell and spatial transcriptomicsNeuroinflammation and Neurodegeneration MechanismsBiologyNeural stem cellSubventricular zoneCell biologyTranscription factorDownregulation and upregulationStem cellPopulationTranscriptomeNeuroscience

MeSH terms

AnimalsBrain InjuriesCell DifferentiationBrain IschemiaInterferon-gammaMaleMice, Inbred C57BLTranscription, GeneticCell LineageGene Expression ProfilingNeural Stem CellsSingle-Cell Analysis

Funding

  • Deutsches Krebsforschungszentrum
  • National Science Council
  • Universitätsklinikum Heidelberg
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