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Robert J. Lefkowitz

Howard Hughes Medical InstituteORCID https://orcid.org/0000-0003-1472-7545
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Top Publications

Seven-transmembrane receptors
Nature Reviews Molecular Cell Biology20022,659 citations
Turning off the signal: desensitization of β‐adrenergic receptor function
The FASEB Journal19901,256 citations
The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals
Journal of Cell Science20021,109 citations
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
Trends in Pharmacological Sciences1993805 citationsFirst authorCorresponding
β-arrestin-mediated receptor trafficking and signal transduction
Trends in Pharmacological Sciences2011695 citationsCorresponding
Regulation of tyrosine kinase cascades by G-protein-coupled receptors
Current Opinion in Cell Biology1999690 citationsCorresponding
Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes.
Molecular Pharmacology1982594 citations
β-Arrestin-biased ligands at seven-transmembrane receptors
Trends in Pharmacological Sciences2007587 citationsCorresponding
A Quantitative Analysis of Beta-Adrenergic Receptor Interactions: Resolution of High and Low Affinity States of the Receptor by Computer Modeling of Ligand Binding Data
Molecular Pharmacology1980555 citations
Regulation of G Protein-Coupled Receptor Kinases and Arrestins During Receptor Desensitization
Molecular Pharmacology2003442 citations
Robert J. Lefkowitz · Scinovex