articleTop 1% cited
A Quantitative Analysis of Beta-Adrenergic Receptor Interactions: Resolution of High and Low Affinity States of the Receptor by Computer Modeling of Ligand Binding Data
Molecular Pharmacology · 1980 · Vol. 17(1) · pp. 14–23
Richard S. Kent✉(Howard Hughes Medical Institute)André De Léan(Howard Hughes Medical Institute)Robert J. Lefkowitz(Duke Medical Center)
Receptor Mechanisms and SignalingPharmacological Effects and AssaysMass Spectrometry Techniques and ApplicationsReceptorAgonistAdenylate kinaseCyclaseDissociation constantChemistryLigand (biochemistry)Intrinsic activityAdrenergic receptorBinding site
MeSH terms
Adenylyl CyclasesAdrenergic beta-AgonistsAnimalsAnuraBinding SitesBinding, CompetitiveComputersDihydroalprenololDose-Response Relationship, DrugErythrocyte MembraneLigandsMethodsModels, TheoreticalNucleotidesReceptors, Adrenergic
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References
Properties of [3H]Haloperidol and [3H]Dopamine Binding Associated with Dopamine Receptors in Calf Brain Membranes
Molecular Pharmacology · 1976 · 483 citations
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Journal of Biological Chemistry · 1951 · 317,666 citations
The Binding of Agonists to Brain Muscarinic Receptors
Molecular Pharmacology · 1978 · 676 citations
Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.
American Journal of Physiology-Endocrinology and Metabolism · 1978 · 2,383 citations
Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits<sup>*</sup>
Biochemistry · 1966 · 3,002 citations
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