A review on recent biological and chemical worth of Neem (Azadirachta indica A. Juss)

Abstract

Neem (Azadirachta indica), a useful multipurpose tree species, is a member of the Meliaceae family. Indians have revered Neem for millennia for its use in organic fertilizers, medicines, and pesticides, among other everyday necessities. Neem oil is used to treat worm infections, stomach ulcers and other conditions. Mulch and fertilizer made from Neem leaves and twigs have shown to be effective. Azadirachtin is a systemic insecticide that is extracted from Neem seed oil. Additionally, Neem trees have antibacterial, antiviral, anti-inflammatory, antifungal, and antiallergic properties. Biodiesel is also made from Neem seeds. Biodiesel is the alternative fuel that is most similar to diesel engines. Numerous compounds isolated from Neem have been shown to inhibit the SARS-CoV-2 (COVID-19) PLpro protein.